Atopic Dermatitis (Eczema): Pathophysiology, ICD-10 L20 & JAK Inhibitor Protocols
Clinical Definition Eczema, clinically referred to as Atopic Dermatitis (AD), is a chronic, relapsing, pruritic inflammatory dermatosis. It involves a complex interplay of skin barrier dysfunction (e.g., Filaggrin mutations) and immune dysregulation (Th2 pathway activation). The condition manifests morphologically in stages: acute (vesiculation, erythema), subacute (excoriation, crusting), and chronic (lichenification). It is the cutaneous manifestation…