Enteroviral vesicular stomatitis

Clinical Definition Hand, Foot, and Mouth Disease (HFMD) is a common systemic viral infection characterized by vesicular exanthema on the palms, soles, and buttocks, accompanied by oral enanthem (ulcerative stomatitis). It is predominantly caused by the Enterovirus genus, specifically Coxsackievirus A16 (CV-A16) and Enterovirus 71 (EV-A71). While typically self-limiting, EV-A71 infections are notably associated with…