Lisinopril: Mechanism of Action (ACE Inhibition), RAAS Kinetics & Indications
Quick Facts Summary Key Parameter Pharmacological Data Pharmacologic Class Angiotensin-Converting Enzyme (ACE) Inhibitor ATC Code C09AA03 Primary Mechanism Competitive inhibition of ACE, reducing Angiotensin II synthesis. Key Distinguisher Not a prodrug; not metabolized by the liver. Black Box Warning Fetal Toxicity (Pregnancy Category D) Detailed Clinical Profile Lisinopril is a synthetic peptide derivative and a…