Atorvastatin Calcium: Clinical Pharmacology, Mechanism of Action (MOA) & Pharmacokinetics
Pharmacological Classification Class: HMG-CoA Reductase Inhibitor (Statin); Lipid-altering agent. ATC Code: C10AA05 (Cardiovascular system > Lipid modifying agents > HMG CoA reductase inhibitors) Common Trade Names: Lipitor (Note: Various generics available). Mechanism of Action (MOA) Atorvastatin is a selective, competitive inhibitor of 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase. This enzyme is the rate-limiting catalyst responsible for the…