Comprehensive database of drug classifications. Review pharmacodynamics, pharmacokinetic profiles, and mechanisms of action (MOA) for generic pharmaceutical compounds.
Quick Facts Summary Key Parameter Pharmacological Data Pharmacologic Class Angiotensin-Converting Enzyme (ACE) Inhibitor ATC Code C09AA03 Primary Mechanism Competitive inhibition of ACE, reducing Angiotensin II synthesis. Key Distinguisher Not a prodrug; not metabolized by the liver. Black Box Warning Fetal Toxicity (Pregnancy Category D) Detailed Clinical Profile Lisinopril is a synthetic peptide derivative and a…
Pharmacological Classification Class: HMG-CoA Reductase Inhibitor (Statin); Lipid-altering agent. ATC Code: C10AA05 (Cardiovascular system > Lipid modifying agents > HMG CoA reductase inhibitors) Common Trade Names: Lipitor (Note: Various generics available). Mechanism of Action (MOA) Atorvastatin is a selective, competitive inhibitor of 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase. This enzyme is the rate-limiting catalyst responsible for the…
Pharmacological Classification Class: Glucagon-Like Peptide-1 (GLP-1) Receptor Agonist; Incretin Mimetic. ATC Code: A10BJ06 (Drugs used in diabetes > Blood glucose lowering drugs, excluding insulins > Glucagon-like peptide-1 (GLP-1) analogues). Common Trade Names: Ozempic, Wegovy, Rybelsus (Reference only; indications vary by trade name). Mechanism of Action (MOA) Semaglutide is a selective GLP-1 receptor agonist with 94%…
Pharmacological Classification Class: Biguanide ATC Code: A10BA02 Mechanism of Action (MOA) Metformin’s primary antihyperglycemic effect is achieved through the activation of AMP-activated protein kinase (AMPK), a key enzyme in cellular energy homeostasis. This activation leads to several downstream effects. In the liver, it inhibits hepatic gluconeogenesis and glycogenolysis, effectively reducing the endogenous production of glucose….
Coronary Angiography: Diagnostic Protocol & Technical Specifications Procedure Overview & Indications Coronary Angiography (Cardiac Catheterization) is an invasive diagnostic imaging procedure that utilizes radiopaque contrast media and fluoroscopic X-ray technology to visualize the lumen of the coronary arteries and cardiac chambers. It remains the gold standard for the anatomical assessment of Coronary Artery Disease (CAD)….